Accidents with venomous animals increased 33% from 2004 to 2010 (Ministério da Saúde, 2010). Accidents with multiple stings of Apis gender bees are common in the americas and are estimated to cause between 300 and 400 deaths/year. A single prick can lead to anaphylactic shock in sensitized people, and this reaction is not dose-dependent. It is estimated that a dose of 20 stents/Kg is fatal for humans and animals. It is estimated that 15,000 bees atack occur per year, only in Brazil, causing about 140 deaths. Even non-lethal accidents can cause permanent damage to various organs.
Bee antivenom serum production in large quantities, applicable in Human and Veterinary medicine for the treatment of multiple bites poisoning.
Marco Antonio Stephano
Jorge Elias Kalil
Hisako Gondo Higashi
Rosalvo Guidolin
José Roberto Marcelino
Josefina Farina Morais
Celso Pereira Caricati
Keity Souza Santos
Fabio Fernandes Morato Castro