Caries and periodontal diseases were considered the main oral diseases by the WHO. In industrialized countries, 60-90% of school-age children are affected by caries (Petersen PE, 2002). Although fluoride has been used effectively since 1950, excessive ingestion in the developmental phase of teeth can lead to fluorosis (Whelton HP, 2004). Ingestion of fluoride by children aged 1.5 to 2 years is, on average, between 30 and 80% above the recommendation, and the ingestion of toothpaste corresponds to 55% (Lima YB, 2001).
Composition for oral hygiene (dentifrice) gel with maximum fluorine content of 750ppm (48% reduction of F) and preferential pH of 4.5.
- "Liquid" formulation - allows greater control over the dosage;
- reduced pH facilitates enamel strengthening;
- Reduction of more than 50% in fluorine concentration (reduction of costs).
- Treatment of dental caries;
- Prevention and treatment of dental fluorosis;
- Efficacy equal to or greater than commercial dentifrices.
Agência Unesp de Inovação
Tel: +55 11 5627.0696
Fabiano Vieira Vilhena
Marilia Afonso Rabelo Buzalaf