Cancer, or malignant neoplasms are generic names for a cluster
Plant-derived compounds which possess citomoduladora action and maybe promising drugs for the treatment of cancer and other diseases. The compounds presents: 90% experimental in vivo inhibition of tumor growth against 52% commercial standard gold compound (25mg i.p. dose); low toxicity to the gastrointestinal tract; reduction of adverse effects such as nausea; apoptosis rate of 88%; Cl50 lower than 1μg / mL (reduction of production cost); 57 X increase in the DNA fragmentation rate of malignant cells; greater effectiveness in the fight against neoplasia.
Manoel Odorico de Moraes
Claudia Do Ó Pessoa
Letícia Veras Costa
Lotufo Paulo
Michel Pinheiro Ferreira