Array

UNESP
AUIN | Agência Unesp de Inovação
   

Tecnology

  NEW DRUG CLASS FOR TUBERCULOSIS TREATMENT  

Carimbo Unesp

Attractive

Low Complexity

Band Aid
New Materials
Human Health
PROBLEM

 

The current disease treatment takes too long and require the administration of lots of pills, causing to have high abandon rates by patients. The incomplete treatment favors the appearing of new resistance disease cases, which increases drastically the costs with the treatment and population mortality. For more than 40 years it has not been developed a new drug against tuberculosis (TB Alliance Annual Report, 2009).

 

 

SOLUTION

 

The developed compounds has shown to be effective, in vitro, against the main agent that causes Tuberculosis, Mycobacterium tubercolosis, sensible to the current therapeutic schema, as well as the isolated mono and Multi-drug-resistance clinics.

 

Benefits: The developed compounds present high inhibitory activity against M. tuberculosis, so efficient or better than best currently used medicines for the treatment (rifampicin, isoniazid, ethambutol and pyrazinamide), with fewer citotoxic effects in in vitro experiments, in macrofagos cells culture. The biggest differential is the possibility of acting over current drugs resistant strains. The usage of compounds would bring countless benefits, such as:

 

- Efficient treatment against tuberculosis and possible treatment against resistant tuberculosis;

 

- Reduction in treatment time;

 

- With greater efficiency and lower time, the new drug should lower the treatment abandon and costs.

 

 


Idea

Laboratory

Prototype

Scheduling

Market
Agency Code
09NIT024
Patent
PI0902923-0

Agência Unesp de Inovação

Tel: +55 11 5627.0696

auin@unesp.br

https://auin.unesp.br

Date of deposit
10/08/2009
Inventor(s)

Clarice Queico Fujimura Leite

Maria Helvecia Torre Guayta

Dinorah Gambino Vedani

Fernando Rogério Pavan

Maria Belen Tarallo Dovat

EDITAIS ABERTOS
Editais abertos e histórico de chamamentos públicos

[PodInovar] Parceria com AUIN é fundamental no desenvolvimento de eventos de tecnologia e empreendedorismo, destaca coordenadora do IBIT

15/07/2019 10:40
  download Podcast Unesp: 20190715ibit2-m5_u28_15072019115951.mp3
REPOSITÓRIO INSTITUCIONAL

Acesse aqui os registros de patentes da UNESP

ALUMNI

Portal do ex-aluno

Facebook AUIN Unesp Youtube AUIN Unesp Instagram AUIN Unesp